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During the early stages of limb and fin regeneration in aquatic vertebrates (i.e., fishes and amphibians), blastema undergo transcriptional rewiring of innate immune signaling pathways to promote immune cell recruitment. In mammals, a fundamental component of innate immune signaling is the cytosolic DNA sensing pathway, cGAS‐STING. However, to what extent the cGAS‐STING pathway influences regeneration in aquatic anamniotes is unknown. In jawed vertebrates, negative regulation of cGAS‐STING activity is accomplished by suppressors of cytosolic DNA such as Trex1, Pml, and PML‐like exon 9 (Plex9) exonucleases. Here, we examine the expression of these suppressors of cGAS‐STING, as well as inflammatory genes and cGAS activity during caudal fin and limb regeneration using the spotted gar (Lepisosteus oculatus) and axolotl (Ambystoma mexicanum) model species, and during age‐related senescence in zebrafish (Danio rerio). In the regenerative blastema of wounded gar and axolotl, we observe increased inflammatory gene expression, including interferon genes and interleukins 6 and 8. We also observed a decrease in axolotlTrex1and garpmlexpression during the early phases of wound healing which correlates with a dramatic increase in cGAS activity. In contrast, theplex9.1gene does not change in expression during wound healing in gar. However, we observed decreased expression ofplex9.1in the senescing cardiac tissue of aged zebrafish, where 2′3′‐cGAMP levels are elevated. Finally, we demonstrate a similar pattern ofTrex1,pml, andplex9.1gene regulation across species in response to exogenous 2′3′‐cGAMP. Thus, during the early stages of limb‐fin regeneration, Pml, Trex1, and Plex9.1 exonucleases are downregulated, presumably to allow an evolutionarily ancient cGAS‐STING activity to promote inflammation and the recruitment of immune cells.

Ocean heat exchanges at the marginal ice zone (MIZ) play an important role in melting sea ice. Mixed‐layer eddies transport heat and ice floes across the MIZ, facilitating the pack's access to warm waters. This study explores these frontal dynamics using disk‐shaped floes coupled to an upper‐ocean model simulating the sea ice edge. Numerical experiments reveal that small floes respond more strongly to fine‐scale ocean currents, which favors higher dispersion rates and weakens sea ice drag onto the underlying ocean. Floes with radii smaller than resolved turbulent filaments (∼2–4 km) result in a wider and more energetic MIZ, by a factor of 70% each, compared to larger floes. We hypothesize that this floe size dependency may affect sea ice break‐up by controlling oceanic energy propagation into the MIZ and modulate the sea ice pack's melt rate by regulating lateral heat transport toward the sea ice cover.

Variability in oceanic conditions directly impacts ice loss from marine outlet glaciers in Greenland, influencing the ice sheet mass balance. Oceanic conditions are available from Atmosphere‐Ocean Global Climate Model (AOGCM) output, but these models require extensive computational resources and lack the fine resolution needed to simulate ocean dynamics on the Greenland continental shelf and close to glacier marine termini. Here, we develop a statistical approach to generate ocean forcing for ice sheet model simulations, which incorporates natural spatiotemporal variability and anthropogenic changes. Starting from raw AOGCM ocean heat content, we apply: (a) a bias‐correction using ocean reanalysis, (b) an extrapolation accounting for on‐shelf ocean dynamics, and (c) stochastic time series models to generate realizations of natural variability. The bias‐correction reduces model errors by ∼25% when compared to independent in‐situ measurements. The bias‐corrected time series are subsequently extrapolated to fjord mouth locations using relations constrained from available high‐resolution regional ocean model results. The stochastic time series models reproduce the spatial correlation, characteristic timescales, and the amplitude of natural variability of bias‐corrected AOGCMs, but at negligible computational expense. We demonstrate the efficiency of this method by generating >6,000 time series of ocean forcing for >200 Greenland marine‐terminating glacier locations until 2100. As our method is computationally efficient and adaptable to any ocean model output and reanalysis product, it provides flexibility in exploring sensitivity to ocean conditions in Greenland ice sheet model simulations. We provide the output and workflow in an open‐source repository, and discuss advantages and future developments for our method.

Melt rates of West Antarctic ice shelves in the Amundsen Sea track large decadal variations in the volume of warm water at their outlets. This variability is generally attributed to wind‐driven variations in warm water transport toward ice shelves. Inspired by conceptual representations of the global overturning circulation, we introduce a simple model for the evolution of the thermocline, which caps the warm water layer at the ice‐shelf front. This model demonstrates that interannual variations in coastal polynya buoyancy forcing can generate large decadal‐scale thermocline depth variations, even when the supply of warm water from the shelf‐break is fixed. The modeled variability involves transitions between bistable high and low melt regimes, enabled by feedbacks between basal melt rates and ice front stratification strength. Our simple model captures observed variations in near‐coast thermocline depth and stratification strength, and poses an alternative mechanism for warm water volume changes to wind‐driven theories.

In recent years, the Southern Ocean has experienced unprecedented surface warming and sea ice loss—a stark reversal of the sea ice expansion and surface cooling that prevailed over the preceding decades. Here, we examine the mechanisms that led to the abrupt circumpolar surface warming events that occurred in late 2016 and 2019 and assess the role of internal climate variability. A mixed layer heat budget analysis reveals that these recent circumpolar surface warming events were triggered by a weakening of the circumpolar westerlies, which decreased northward Ekman transport and accelerated the seasonal shoaling of the mixed layer. We emphasize the underappreciated effect of the latter mechanism, which played a dominant role and amplified the warming effect of air–sea heat fluxes during months of peak solar insolation. An examination of the CESM1 large ensemble demonstrates that these recent circumpolar warming events are consistent with the internal variability associated with the Southern Annular Mode (SAM), whereby negative SAM in austral spring favors shallower mixed layers and anomalously high summertime SST. A key insight from this analysis is that the seasonal phasing of springtime mixed layer depth shoaling is an important contributor to summertime SST variability in the Southern Ocean. Thus, future Southern Ocean summertime SST extremes will depend on the coevolution of mixed layer depth and surface wind variability.

Surface ocean temperature and velocity anomalies at meso‐ and sub‐meso‐scales induce wind stress anomalies. These wind‐front interactions, referred to as thermal (TFB) and current (CFB) feedbacks, respectively, have been studied in isolation at mesoscale, yet they have rarely been considered in tandem. Here, we assess the combined influence of TFB and CFB and their relative impact on surface wind stress derivatives. Analyses are based on output from two regions of the Southern Ocean in a coupled simulation with local ocean resolution of 2 km. Considering both TFB and CFB shows regimes of interference, which remain mostly linear down to the simulation resolution. The jointly‐generated wind stress curl anomalies approach 10⁻⁵ N m⁻³, ∼20 times stronger than at mesoscale. The synergy of both feedbacks improves the ability to reconstruct wind stress curl magnitude and structure from both surface vorticity and SST gradients by 12%–37% on average, compared with using either feedback alone.

Arctic sea ice extent continues to decline at an unprecedented rate that is commonly underestimated by climate projection models. This disagreement may imply biases in the representation of processes that bring heat to the sea ice in these models. Here we reveal interactions between ocean-ice heat fluxes, sea ice cover, and upper-ocean eddies that constitute a positive feedback missing in climate models. Using an eddy-resolving global ocean model, we demonstrate that ocean-ice heat fluxes are predominantly induced by localized and intermittent ocean eddies, filaments, and internal waves that episodically advect warm subsurface waters into the mixed layer where they are in direct contact with sea ice. The energetics of near-surface eddies interacting with sea ice are modulated by frictional dissipation in ice-ocean boundary layers, being dominant under consolidated winter ice but substantially reduced under low-concentrated weak sea ice in marginal ice zones. Our results indicate that Arctic sea ice loss will reduce upper-ocean dissipation, which will produce more energetic eddies and amplified ocean-ice heat exchange. We thus emphasize the need for sea ice-aware parameterizations of eddy-induced ice-ocean heat fluxes in climate models.

The export of Antarctic Bottom Water (AABW) supplies the bottom cell of the global overturning circulation and plays a key role in regulating climate. This AABW outflow must cross, and is therefore mediated by, the Antarctic Circumpolar Current (ACC). Previous studies present widely varying conceptions of the role of the ACC in directing AABW across the Southern Ocean, suggesting either that AABW may be zonally recirculated by the ACC, or that AABW may flow northward within deep western boundary currents (DWBC) against bathymetry. In this study the authors investigate how the forcing and geometry of the ACC influences the transport and transformation of AABW using a suite of process-oriented model simulations. The model exhibits a strong dependence on the elevation of bathymetry relative to AABW layer thickness: higher meridional ridges suppress zonal AABW exchange, increase the strength of flow in the DWBC, and reduce the meridional variation in AABW density across the ACC. Furthermore, the transport and transformation vary with density within the AABW layer, with denser varieties of AABW being less efficiently transported between basins. These findings indicate that changes in the thickness of the AABW layer, for example, due to changes in Antarctic shelf processes, and tectonic changes in the sea floor shape may alter the pathways and transformation of AABW across the ACC.